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method of obtaining biocompatible organic nanostructures, biocompatible organic nanostructures, agrochemical composition and their uses

机译:获得生物相容性有机纳米结构的方法,生物相容性有机纳米结构,农用化学成分及其用途

摘要

Method for Obtaining Biocompatible Organic Nanostructures, Biocompatible Organic Nanostructures, Agrochemical Composition and Their Uses The present invention is for a method of obtaining biocompatible organic nanostructures by the steps of (a) preparing an aqueous solution with high concentration of micronutrients and / or nutritional elements and controlled temperatures and pressure; (b) adding the encapsulation system to the aqueous solution of step (a) in a ratio of from 3.0% to 20.0% by weight of the final mixture, under slow agitation at 30 to 60 rpm, wherein the encapsulation system It is composed of natural, synthetic and / or semi-synthetic phospholipids and, optionally, surfactants, stabilizing organic elements, among others; (c) a first mechanical agitation for about 30 to 120 minutes at speeds between 20 and 60 rpm and then a second agitation at speeds greater than 1,300 rpm and a pressure greater than 5 bar until complete homogenization and, returning mixing at the conditions of the first stirring at ambient pressure; (d) cooling the mixture to temperatures below 20 ° C for about 3 to 6 hours, (e) diluting the mixture to about 15 to 50% of the final total solids concentration and (f) adding non-toxic microbiological preservatives . In addition, the patent application relates to a biocompatible organic nanostructure obtained by the method described above, said nanostructure comprising natural, synthetic and / or semi-synthetic phospholipids and optionally surfactants, water soluble and organic stabilizing elements and / or agents. non-toxic microbiological preservatives. Also, the invention provides an agrochemical composition containing said nanostructure of the present invention and its uses in the agricultural environment as vectors of transport of bioactive substances.
机译:获得生物相容性有机纳米结构的方法,生物相容性有机纳米结构,农药组合物及其用途本发明涉及一种通过以下步骤获得生物相容性有机纳米结构的方法:(a)制备高浓度的微量营养素和/或营养元素的水溶液,以及控制温度和压力; (b)在30至60 rpm的缓慢搅拌下,以最终混合物重量的3.0%至20.0%的比例将包封系统添加到步骤(a)的水溶液中,其中包封系统包括:天然,合成和/或半合成的磷脂,以及可选地,表面活性剂,稳定有机元素等; (c)第一次以20至60 rpm的速度进行机械搅拌约30至120分钟,然后以大于1300 rpm的速度和大于5 bar的压力进行第二次搅拌直至完全均质化,并在首先在环境压力下搅拌; (d)将混合物冷却至20°C以下的温度约3至6小时,(e)将混合物稀释至最终总固体浓度的15%至50%,并(f)添加无毒的微生物防腐剂。另外,该专利申请涉及通过上述方法获得的生物相容性有机纳米结构,所述纳米结构包含天然,合成和/或半合成的磷脂和任选的表面活性剂,水溶性和有机稳定剂和/或试剂。无毒的微生物防腐剂。另外,本发明提供了包含本发明的所述纳米结构的农用化学组合物及其在农业环境中作为生物活性物质运输载体的用途。

著录项

  • 公开/公告号BR102018007663A2

    专利类型

  • 公开/公告日2019-10-29

    原文格式PDF

  • 申请/专利权人 DUETTO COMÉRCIO E DISTRIBUIÇÃO LTDA;

    申请/专利号BR20181007663

  • 发明设计人 GIUSEPPE MÁRIO MERENNA;

    申请日2018-04-16

  • 分类号C05G1;A01N25/28;B01J13;B82Y40;

  • 国家 BR

  • 入库时间 2022-08-21 12:03:36

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