首页> 外国专利> {6 - (e) -3- {methyl (3-methyl-1-benfofuran-2-yl) methyl amino) -3-xopro-1-en-1-yl dihydrogen phosphate use -2-oxo-3,4-dihydro-1,8-naphthyridin-1 (2h) -yl} methyl and pharmaceutical composition for treating bacterial infections associated with diabetic foot

{6 - (e) -3- {methyl (3-methyl-1-benfofuran-2-yl) methyl amino) -3-xopro-1-en-1-yl dihydrogen phosphate use -2-oxo-3,4-dihydro-1,8-naphthyridin-1 (2h) -yl} methyl and pharmaceutical composition for treating bacterial infections associated with diabetic foot

机译:{6-[[(e))-3- {甲基[(3-甲基-1-苯呋喃-2-基)甲基]氨基)-3-xopro-1-en-1-基]磷酸二氢盐使用-2-氧-3,4-二氢-1,8-萘啶-1(2h)-基}甲基和用于治疗与糖尿病足相关的细菌感染的药物组合物

摘要

The present invention relates to means and methods for treating diabetic foot infections. specifically, drug compounds are provided which combine a high therapeutic activity against staphylococcus ssp bacteria. with a high degree of bone penetration and vasodilation effects. This unique combination of properties allows for high local concentrations of the drug at the site of infection even in diabetic foot patients who typically have poor blood perfusion at the site of infection.
机译:本发明涉及治疗糖尿病足感染的手段和方法。具体而言,提供了结合了针对葡萄球菌ssp细菌的高治疗活性的药物化合物。具有高度的骨渗透和血管舒张作用。这种独特的特性组合使得即使在感染部位血液灌流通常较差的糖尿病足患者中,也可以在感染部位获得较高的局部药物浓度。

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