Use of a fasting simulated diet to increase the effectiveness of antiestrogens in cancer therapy

摘要

A compound with antiestrogenic activity is used in a method for treating bc or other estrogen responsive tumors in a human patient, wherein the method comprises subjecting the patient to a simulated fasting diet for a period of 24-190 hours while The patient is being treated with the compound having antiestrogenic activity, which may be a selective estrogen receptor modulator (serm), a selective estrogen receptor infra-regulator (serd) or an aromatase inhibitor (ai).