首页> 外国专利> methods for detecting the presence of at least one pathogenic bordetella species and selecting a patient exhibiting pertussis-like symptoms, and kit for detecting the presence of at least one pathogenic bordetella species.

methods for detecting the presence of at least one pathogenic bordetella species and selecting a patient exhibiting pertussis-like symptoms, and kit for detecting the presence of at least one pathogenic bordetella species.

机译:种方法,用于检测至少一种致病性球菌种类并选择表现出百日咳样症状的患者,以及用于检测至少一种致病性球菌种类的试剂盒。

摘要

The present disclosure relates to methods for determining whether a patient exhibiting pertussis-like symptoms will benefit from treatment with therapeutic agents that inhibit bordetella holmesii. These methods are based on the detection of bordetella pertussis, bordetella parapertussis and bordetella holmesii in a biological sample by assessing the presence of the target repeating elements is481, is1001 and his1001, respectively. Kits for use in practicing the methods are also provided.
机译:本公开涉及用于确定表现出百日咳样症状的患者是否将从抑制霍曼氏杆菌的治疗剂的治疗中受益的方法。这些方法是基于分别评估目标重复元件is481,is1001和his1001的存在,从而检测生物样品中的百日咳博德特氏菌,副百日咳博德特氏菌和霍姆氏博德特氏菌。还提供了用于实施该方法的试剂盒。

著录项

  • 公开/公告号BR112018069316A2

    专利类型

  • 公开/公告日2019-01-22

    原文格式PDF

  • 申请/专利权人 QUEST DIAGNOSTICS INVESTMENTS LLC;

    申请/专利号BR20181169316

  • 发明设计人 JULES CHEN;MICHELLE TABB;

    申请日2017-03-23

  • 分类号C07H21;C07H21/04;

  • 国家 BR

  • 入库时间 2022-08-21 12:03:26

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