method for preparing an oxy133 polymorph, oxy133 polymorph, and pharmaceutical composition.

摘要

Compositions and methods for preparing an oxy133 polymorph are provided. such compositions and methods include subjecting an oxy133 slurry to conditions sufficient to convert oxy133 to polymorphic form a, polymorphic form b, polymorphic form c, polymorphic form d, polymorphic form f, polymorphic form g, polymorphic form h, polymorphic form i of oxy133 or a mixture thereof. an oxy133 polymorph is also provided and such polymorph may be polymorphic form a, polymorphic form b, polymorphic form c, polymorphic form d, polymorphic form e, polymorphic form g, polymorphic form h, polymorphic form i or a mixture of them. Also provided are pharmaceutical compositions which include oxy133 polymorphs.