graft polymer, methods for preparing a graft polymer, for preparing a dispensing system and for preventing, treating or ameliorating a medical disorder, composition, soft tissue filler, use of a graft polymer, and kit .

摘要

The present invention is directed to a novel graft polymer of a hyaluronic acid polymer and n-isopropylacrylamide-based polymer, preparations, compositions and uses thereof. in particular, the invention relates to ph and / or temperature sensitive compositions capable of spontaneously forming nanoparticles useful as active and dispensing agents and systems for at least one bioactive agent.