amanita toxin derivatives and their conjugation to a cell binding molecule

摘要

Amanita toxin derivatives of formula (I) wherein formula (a) is (1) r1, r2, r3, r4, r5, r6, r7, r8, r9, r10, x, l, m, n and q are defined herein. the preparation of derivatives. therapeutic use of derivatives in the targeted treatment of cancer, autoimmune disorders and infectious diseases.