SEPSE TREATMENT METHODS WITH CHEMICAL BINDING CONNECTIONS 2A AND / OR 2B

摘要

methods of treating sepsis-induced brain dysfunction (sibd), comprising administering a synaptic vesicle-binding chemical entity 2a and / or 2b to an individual with sepsis. methods for reducing sepsis mortality, comprising administering a synaptic vesicle-binding chemical entity 2a and / or 2b to an individual with sepsis. in some embodiments, the synaptic vesicle binding entity 2a and / or 2b is a synaptic vesicle modulator 2a and / or 2b, such as agonist, partial agonist, antagonist or partial antagonist. in some embodiments, the synaptic vesicle binding chemical entity 2a and / or 2b is levetiracetam or a levetiracetam derivative or analog. in some embodiments, the synaptic vesicle binding chemical entity 2a is levetiracetam.