hydrogel and osmotic combined cervical dilators and manufacturing method

摘要

a cervical dilator including a stem comprising a partially or fully dehydrated hydrogel comprising a water insoluble synthetic hydrophilic polymer capable of radial expansion due to the absorption of water from a body fluid. The cervical dilator softens and enhances the cervical tissue and expands the cervical canal by a combined action of radial hydrogel stem expansion and osmotic removal of water from the tissue. Osmotic withdrawal is caused by at least one osmotically active compound, such as a soluble salt, a polyelectrolyte, or a mixture thereof, characterized in that at least one osmotically active compound is dispersed in the hydrogel. The cervical dilator may also include a non-toxic hydrogel plasticizer such as water.