tablet comprising sevelamer carbonate and sodium chloride, and use of a tablet

摘要

A tablet comprising a carbonate salt of an aliphatic amine polymer, compositions and method for removing phosphate from a patient in need thereof. The tablets, compositions and methods of the present invention comprising a carbonate salt of a monovalent anion aliphatic amine polymer can prevent or ameliorate acidosis, particularly acidosis in patients with kidney disease. The tablets and compositions of the present invention maintain a disintegration time no greater than 30 minutes at 37 ° C and at a pH of at least 1 over a period of at least ten weeks at 60 ° C. In addition, the tablets are stable for extended periods of time without the need for specialized storage conditions.