INSERSIBLE EYE IMPLANT IN AN EYE LUMEN AND DISTRIBUTION METHOD OF A THERAPEUTIC AGENT TO AN EYE

摘要

nasolacrimal drainage system implants for pharmacotherapy. Implant devices, systems and methods for insertion into a puncture point of a patient optionally comprises a drug core and a coating body disposed on the drug core. The drug core includes a therapeutic agent that can be delivered to the eye, and the coating defines at least one exposed surface of the drug core. The exposed surface (s) of the drug core may contact a tear or tear of the membrane membrane and release the therapeutic agent at therapeutic levels during a controlled period when the implant is implanted for use. The implant may include a retention member for retaining the drug core and casing body near the puncture point, optionally comprising an elastically expandable shape memory alloy. an occlusive member may be attached to the retaining member to at least partially occlude the flow of tears through the canalicular lumen.