conjugates and hpma-docetaxel or gemcitabine and their uses

摘要

hpma-docetaxel or gemcitabine conjugate compounds and use thereof The present invention relates to water-soluble coccations of gemcitabine and docetaxel formed by conjugating gemcitabine or docetaxel to a water-soluble polymer such as n-2-hydroxypropyl methacrylamide ( hpma). Methods of using the compositions of the invention for treating cancer are also described.