首页> 外国专利> compound or a salt thereof, compound methanesulfonate, compound sulfate, farm composition, aceutic composition, phosphatidyl isitol 3-kinase inhibitors, and mammalian target of rapamycin, and use of a compound

compound or a salt thereof, compound methanesulfonate, compound sulfate, farm composition, aceutic composition, phosphatidyl isitol 3-kinase inhibitors, and mammalian target of rapamycin, and use of a compound

机译:化合物或其盐,化合物甲磺酸盐,化合物硫酸盐,农用组合物,乙酰乙酸盐组合物,磷脂酰肌醇3-激酶抑制剂和雷帕霉素的哺乳动物靶标,以及该化合物的用途

摘要

There is provided a novel compound that inhibits phosphatidylinositol 3-kinase (PI3K) and/or the mammalian target of rapamycin (mTOR) and exhibits anti-tumor activity. The present invention provides a compound represented by the following formula (1) having various substituents that inhibits PI3K and/or mTOR and exhibits anti-tumor activity: wherein R 1 , R 2 , R 3 , R 4 , R a , R b , R c , and X each have the same meanings as defined in the specification.
机译:提供了一种新颖的化合物,其抑制磷脂酰肌醇3-激酶(PI3K)和/或雷帕霉素的哺乳动物靶标(mTOR)并表现出抗肿瘤活性。本发明提供由下式(1)表示的化合物,其具有各种取代基,这些取代基抑制PI3K和/或mTOR并显示出抗肿瘤活性:其中R 1,R 2,R 3,R 4,R a,R b,R c和X各自具有与说明书中定义的相同含义。

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