首页> 外国专利> 'Process for the preparation of etoricoxib, compound, process for the purification of etoricoxib, polymorphic form, etoricoxib'

'Process for the preparation of etoricoxib, compound, process for the purification of etoricoxib, polymorphic form, etoricoxib'

机译:“制备依托昔布的方法,化合物,依托昔布的纯化方法,多晶型物,依托昔布”

摘要

The present invention provides a improved process for preparing Etoricoxib using substituted ²-chlorovinaniidinium salts containing a cyclic group, optionally containing a heteroatom. The present invention also provides a process for the preparation of the intermediate ²-chlorovinamidinium salts. In one of the embodiments is provided a process for the purification of Etoricoxib as well as the intermediates.
机译:本发明提供了一种改进的制备埃托考昔的方法,该方法使用了含有环状基团,任选地含有杂原子的取代的2-氯乙烯基ani鎓盐。本发明还提供了制备中间体2-氯乙烯基ami盐的方法。在一个实施方案中,提供了一种纯化埃托考昔及其中间体的方法。

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