Isotope-3-il-carboxamidas and its preparation and use. （Divisional request 201803065）

摘要

p ISOQUINOLINE COMPOUNDS ARE DISCLOSED FOR THE TREATMENT OF VARIOUS DISEASES AND PATHOLOGIES. MORE SPECIFICALLY, THE PRESENT INVENTION REFERS TO THE USE OF A COMPOUND OF ISOQUINOLINE, OR ANALOGUES THEREOF, IN THE TREATMENT OF DISORDERS CHARACTERIZED BY THE ACTIVATION OF THE SENTILDE; ALIZACIOcute; n A WNT (FOR EXAMPLE, CAacute; NCER, ABNORMAL CELL PROLIFERATION, ANGIOGEacute; NESIS, FIBROATIC, LAKE AND BONE DISEASES, AND ARTHROSIS),THE MODULATION OF CELLULAR EVENTS MEDIATED BY THE SENTILDE; ALIZATION OF THE WAY TO WNT, ASIacute; LIKE GENETIC DISEASES AND CONDITIONS / DISORDERS / NEUROLOATIC DISEASES DUE TO MUTATIONS OR THE POOR REGULATION OF THE WNT AND / OR ONE OR MORE MAINTENANCE OF THE COMPONENTS OF SENTILT. ALSO ARE PROVIDED FOR TREATING PATHOLOGICAL STATES RELATED TO WNT. /p