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Guanine analogues such as telomerase substrates and telomere length influencers
Guanine analogues such as telomerase substrates and telomere length influencers
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机译:鸟嘌呤类似物,例如端粒酶底物和端粒长度影响因子
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摘要
This invention relates to compounds useful for inhibiting telomere elongation. More specifically, the invention provides nucleotide analogs that are incorporated into telomeres by telomerase thereby inhibiting elongation of telomeres. The compounds are useful in treating cancer and other cell proliferative diseases.
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