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Guanine Analogs as Telomerase Substrates and Telomere Length Affectors
Guanine Analogs as Telomerase Substrates and Telomere Length Affectors
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机译:鸟嘌呤类似物作为端粒酶底物和端粒长度的影响者。
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摘要
This invention relates to compounds useful for inhibiting telomere elongation. More specifically, the invention provides nucleotide analogs that are incorporated into telomeres by telomerase thereby inhibiting elongation of telomeres. The compounds are use in treating cancer and other cell proliferative diseases.
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