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PROCEDURE FOR DETERMINING INSPECTIONS FOR VENTILATION INHOMOGENITY, F.EKS. LCI (LUNG CLEARANCE INDEX) OF A Pediatrician Experienced Person
PROCEDURE FOR DETERMINING INSPECTIONS FOR VENTILATION INHOMOGENITY, F.EKS. LCI (LUNG CLEARANCE INDEX) OF A Pediatrician Experienced Person
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机译:F.EKS,确定通风不均匀性检查的程序。儿科医生有经验者的LCI(肺部清除指数)
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摘要
The present invention relates to a method to determine the lung clearance index (LCI) or other indices of ventilation inhomogeneity of the lungs of a paediatric test subject. Wash-in is used to wash-in the inert tracer gas and the wash-out is conducted by inhaling atmospheric air from the surroundings and exhaling to a confined space such as a collection bag until the end-tidal tracer gas concentration has fallen below a predetermined fraction of the starting concentration. The LCI of a paediatric test subject is calculated as the ratio between the cumulative expired volume (V CE ) required to clear the inert tracer gas concentration from the lungs of the paediatric test subject below a predetermined fraction of the starting concentration and the functional residual capacity (FRC) where FRC is determined by dividing the net volume of inert tracer gas exhaled by said paediatric test subject with the difference in end-tidal fractional concentration of the inert tracer gas at the start and end of the wash-out period; and where V CE is determined by measuring the total volume in the collection bag after completed wash-out period. Furthermore the present invention relates to a corresponding system and computer-readable medium.
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机译:本发明涉及确定儿科测试对象的肺的肺部清除指数(LCI)或其他通气不均匀性指数的方法。冲洗用于冲洗惰性示踪气体,冲洗是通过从周围环境中吸入大气并呼入密闭空间(例如收集袋),直到潮汐末示踪气体浓度降至起始浓度的预定分数。儿科测试对象的LCI计算为从儿科测试对象的肺部清除惰性示踪气体浓度至起始浓度的预定比例以下所需的累积呼出气量(V CE)与功能残余容量之间的比率(FRC),其中FRC是通过用所述儿科测试对象呼出的惰性示踪气体的净体积除以在冲洗期开始和结束时所述惰性示踪气体的潮气末浓度分数的差来确定的; V CE是通过在完成冲洗时间后测量收集袋中的总体积确定的。此外,本发明涉及相应的系统和计算机可读介质。
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