首页> 外国专利> PROCEDURE FOR ASSESSING IF A PATIENT WITH GLIOBLASTOMA MULTIFORM IS SUITABLE FOR IMMUNTERY TREATMENT BASED ON DENDRITIC CELL TUMOR VACCINES

PROCEDURE FOR ASSESSING IF A PATIENT WITH GLIOBLASTOMA MULTIFORM IS SUITABLE FOR IMMUNTERY TREATMENT BASED ON DENDRITIC CELL TUMOR VACCINES

机译:评估胶质母细胞瘤患者是否适合基于树突状细胞瘤疫苗的免疫治疗

摘要

A method of evaluating if a glioblastoma multiforme (GBM) patient is applicable to be treated with an immunotherapy based on dendritic cell tumor vaccines includes a sample obtaining step to obtain a sample from the GBM patient, a detecting step to detect an expression level of a biomarker, and a comparing step to compare the expression level of the biomarker to a threshold, wherein the GBM patient is applicable to treat with the immunotherapy based on dendritic cell tumor vaccines when the expression level of the biomarker is lower than the threshold. A method of prognosticating a survival rate in the GBM patient after a treatment includes a sample obtaining step, a detecting step, and a comparing step, wherein the GBM patient is determined to have a good prognosis after the treatment when the expression level of the sample from the GBM is lower than the threshold.
机译:一种评估多形性胶质母细胞瘤(GBM)患者是否适用于基于树突状细胞瘤疫苗的免疫疗法进行治疗的方法,该方法包括:样品获取步骤,用于从GBM患者中获取样品;检测步骤,用于检测树突​​状细胞瘤的表达水平。生物标志物,以及将生物标志物的表达水平与阈值进行比较的比较步骤,其中当生物标志物的表达水平低于阈值时,GBM患者适用于基于树突状细胞瘤疫苗的免疫治疗。在治疗后对GBM患者的生存率进行预后的方法包括样品获取步骤,检测步骤和比较步骤,其中当样品的表达水平确定为GBM患者在治疗后预后良好来自GBM的阈值低于阈值。

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