MONOCLONAL ANTIBODY OR AN ANTIGEN-BINDING FRAGMENT THEREOF, USES THEREOF, HYBRIDOMA CELL LINE FOR PRODUCTION THEREOF, PHARMACEUTICAL COMPOSITION COMPRISING A MONOCLONAL ANTIBODY OR AN ANTIGEN-BINDING FRAGMENT THEREOF, IN VITRO METHOD FOR THE DIAGNOSIS OF AN AMYLOID-ASSOCIATED DISEASE AND KIT THEREFOR

摘要

The application describes a monoclonal antibody or antigen-binding fragments thereof that bind to AβpGlu(11)-peptides, hybridoma cell lines producing said antibody or fragments thereof, pharmaceutical compositions comprising the same. Furthermore, the application disclosed the uses of said monoclonal antibody and fragments thereof for the diagnosis of amyloidosis, in particular Alzheimer's disease, and related condition, and also for the treatment, prevention or delay of amyloidosis, as well as corresponding methods and kits used therein.