LENTIVIRAL VECTORS PSEUDOTYPED WITH A SINDBIS VIRUS ENVELOPE GLYCOPROTEIN

摘要

Lentiviral vector particles capable of infecting dendritic cells comprising a Sindbis virus E2 glycoprotein variant and a lentiviral vector genome comprising a nucleotide sequence encoding an antigen are provided. Furthermore, pharmaceutical compositions for immunization with said antigen comprising said lentiviral particles and a pharmaceutically acceptable carrier are provided.