SOLUBILIZED CAPSULE FORMULATION OF 1,1-DIMETHYLETHYL (1S)-1-{(2S,4R)-4-(7-CHLORO-4METHOXYISOQUINOLIN-1-YLOXY)-2-({(1R,2S)-1-(CYCLOPROPYLSULFONYL)CARBAMOYL-2-ETHENYLCYCLOPROPYL}CARBAMOYL)PYRROLIDIN-1-YLCARBONYL}-2,2-DIMETHYLPROPYLCARBAMATE

摘要

The present disclosure includes various embodiments directed to a solubilized capsule formulation of asunaprevir, 1,1-dimethylethyl[(1S)-1-{[(2S,4R)-4-(7-chloro-4methoxyisoquinolin-1-yloxy)-2-({(1R,2S)-1-[(cyclopropylsulfonyl)carbamoyl]-2-ethenylcyclopropyl}carbamoyl)pyrrolidin-1-yl]carbonyl}-2,2-dimethylpropyl]carbamate, and to methods including asunaprevir.