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Compositions and methods for protecting organs from ischemia/reperfusion injury associated with transplantation

机译:保护器官免受与移植相关的局部缺血/再灌注损伤的组合物和方法

摘要

The invention provides compositions and methods for protecting organs, such as lungs, from injury associated with transplantation. Specifically, the invention relates to secoisolaricirecinol diglucoside (SDG), including natural SDG, synthetic SDG (LGM2605), (S,S)-SDG, (R,R)-SDG and mixtures thereof, as well as related molecules, for protecting lungs from injury, such as ischemia/reperfusion injury, associated with transplantation.
机译:本发明提供了用于保护器官例如肺免于与移植相关的损伤的组合物和方法。具体而言,本发明涉及癸二异水杨醇二葡萄糖苷(SDG),包括天然SDG,合成SDG(LGM2605),(S,S)-SDG,(R,R)-SDG及其混合物以及相关分子,用于保护肺源于与移植相关的损伤,例如缺血/再灌注损伤。

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