TRISPECIFIC ANTIBODIES AGAINST IL-17A, IL-17F AND ANOTHER PROINFLAMMATORY MOLECULE.

摘要

The present invention relates to the field of biotechnology and proposes monoclonal trispecific binding molecules which specifically bind to human IL-17A, human IL-17F and a human proinflammatory molecule (in particular, TNF-alpha) with a high degree of affinity. The invention also relates to DNA constructs which code for such binding molecules, corresponding expression vectors and production methods, and also treatment methods using said binding molecules.