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COMBINATIONS COMPRISING HISTONE DEACETYLASE INHIBITORS.

机译:包含组氨酸去乙酰化抑制剂的组合。

摘要

The invention relates to a combination of a compound of formula (I) or a pharmaceutically acceptable salt thereof, and at least one second agent selected from the group consisting of proteasome inhibitors, tumour immunotherapeutics or immunomodulatory agents, signal transduction pathway inhibitors, agents inhibiting the BCL2 family of proteins, agents inhibiting Mcl-1, poly (ADP-ribose) polymerase (PARP) Inhibitors, aromatase inhibitors, conventional cytotoxic agents or a miscellaneous agent selected from abiraterone, ARN-509 and MYC inhibitors.
机译:本发明涉及式(I)的化合物或其药学上可接受的盐与至少一种选自蛋白酶体抑制剂,肿瘤免疫治疗剂或免疫调节剂,信号转导途径抑制剂,抑制其的药剂的第二药剂的组合。 BCL2蛋白质家族,抑制Mcl-1的药物,聚(ADP-核糖)聚合酶(PARP)抑制剂,芳香酶抑制剂,常规细胞毒性剂或选自阿比特龙,ARN-509和MYC抑制剂的其他药剂。

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