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ANTI-CCL2 ANTIBODIES FOR TREATMENT OF SCLERODERMA.
ANTI-CCL2 ANTIBODIES FOR TREATMENT OF SCLERODERMA.
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机译:抗CCL2抗体治疗皮肤癣菌。
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摘要
The present invention provides, among other things, improved anti-CCL2 antibodies characterized with high affinity, potency, tissue selectivity and/or epitope specificity, and uses thereof, in particular, for treatment of scleroderma and related fibrotic and/or inflammatory diseases, disorders and conditions. In some embodiments, the present invention provides methods and compositions for treatment of scleroderma and related fibrotic and/or inflammatory diseases, disorders and conditions based on an anti-CCL2 antibody having an affinity of 10-12 M or greater.
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