首页> 外国专利> 5-4-2-5-(1-HYDROXYETHYL)PYRIDIN-2-YLETHOXYPHENYLMETHYL-1 ,3-THIAZOLIDINE- 2,4-DIONE FOR TREATING NONALCOHOLIC FATTY LIVER DISEASE.

5-4-2-5-(1-HYDROXYETHYL)PYRIDIN-2-YLETHOXYPHENYLMETHYL-1 ,3-THIAZOLIDINE- 2,4-DIONE FOR TREATING NONALCOHOLIC FATTY LIVER DISEASE.

机译:5-[[4- [2- [5-(1-(羟乙基)吡啶基-2-基]乙氧基]苯基]甲基] -1,3-噻唑烷-2,4-二酮用于治疗壬酸脂肪肝。

摘要

The present disclosure relates to a method of treating or preventing nonalcoholic fatty liver disease, nonalcoholic steatohepatitis, a chronic granulomatous disorder, a polycystic ovary syndrome, a thyroid carcinoma, a thyroid autoimmune disorder, a pituitary adenoma, atherosclerosis, hypertension, a skin disease, an inflammation and autoimmune disease, and an inflammatory respiratory disease by administering 5-[[4-[2-[5-(1-hydroxyethyl)pyridin-2-yl]ethoxy]phenyl]methyl]- 1,3-thiazolidine-2,4-dione to a subject in need thereof. The disclosure also relates to 5-[[4-[2-[5-(1-hydroxyethyl)pyridin-2-yl]ethoxy]phenyl]methyl]- 1,3-thiazolidine-2,4-dione for use in a pharmaceutical composition or in the manufacture of a medicament for the treatment or prevention of nonalcoholic fatty liver disease or nonalcoholic steatohepatitis.
机译:本公开涉及一种治疗或预​​防非酒精性脂肪肝,非酒精性脂肪性肝炎,慢性肉芽肿性疾病,多囊卵巢综合征,甲状腺癌,甲状腺自身免疫性疾病,垂体腺瘤,动脉粥样硬化,高血压,皮肤病,服用5-[[4- [2- [5-(1-羟乙基)吡啶-2--2-基]乙氧基]苯基]甲基] -1,3-噻唑烷-2可引起炎症和自身免疫疾病,以及炎症性呼吸道疾病,4-二酮对有需要的对象。本发明还涉及5-[[4- [2- [5-(1-羟乙基)吡啶-2-基]乙氧基]苯基]甲基] -1,3-噻唑烷-2,4-二酮。药物组合物或用于治疗或预防非酒精性脂肪肝或非酒精性脂肪性肝炎的药物的制造。

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