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NOVEL ANTI-INFLAMMATORY AGENTS.

机译:新型抗炎剂。

摘要

Disclosed are novel compounds that are useful in regulating the expression of interleukin-6 (IL-6) and/or vascular cell adhesion molecule-1 (VCAM-1), and their use in the treatment and/or prevention of cardiovascular and inflammatory diseases and related disease states, such as, for example, atherosclerosis, asthma, arthritis, cancer, multiple sclerosis, psoriasis, and inflammatory bowel diseases, and autoimmune disease(s). Also, disclosed are compositions comprising the novel compounds, as well as methods for their preparation.
机译:公开了可用于调节白介素-6(IL-6)和/或血管细胞粘附分子-1(VCAM-1)的表达的新型化合物,及其在治疗和/或预防心血管疾病和炎性疾病中的用途以及相关疾病状态,例如动脉粥样硬化,哮喘,关节炎,癌症,多发性硬化症,牛皮癣和炎性肠病以及自身免疫性疾病。另外,公开了包含新型化合物的组合物及其制备方法。

著录项

  • 公开/公告号MX2019007708A

    专利类型

  • 公开/公告日2019-09-04

    原文格式PDF

  • 申请/专利权人 RESVERLOGIX CORP.;

    申请/专利号MX2019007708

  • 发明设计人 HENRIK C. HANSEN;

    申请日2011-09-08

  • 分类号A61K31/517;A61K31/519;A61K31/5377;A61K31/55;A61K31/551;A61P9;C07D239/88;C07D401/04;C07D401/10;C07D401/12;C07D403/10;C07D403/12;C07D409/10;C07D417/06;C07D471/04;

  • 国家 MX

  • 入库时间 2022-08-21 12:01:46

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