USE OF PEPTIDIC DRUGS FOR OSTEOPOROSIS TREATMENT AND BONE REGENERATION.

摘要

The present invention provides osteogenic peptides derived from the Cementum-derived attachment protein (HACD1/CAP) and another derived from the Cementum Protein 1 (CEMP1) and pharmaceutical compositions of these peptides for the prevention and treatment of osteopenia and osteoporosis. These peptides increase bone mineral density in an osteoporotic model and without in vivo side effects, demonstrating clinical effectiveness in the prevention and treatment of osteopenia and osteoporosis in vivo as well as bone repair and/or regeneration.