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METHODS OF TREATING CROHN'S DISEASE AND ULCERATIVE COLITIS.

机译:治疗克罗恩病和溃疡性结肠炎的方法。

摘要

The present disclosure is directed to methods for treating Crohn's disease, and in particular, to methods for inducing clinical remission and/or endoscopic improvement of Crohn's disease, using a JAK1 inhibitor. In certain embodiments, the patient is administered an induction dose of the JAK1 inhibitor to induce clinical remission and/or endoscopic improvement of the Crohn's disease, followed by administration of at least one maintenance dose of the JAK1 inhibitor thereafter. In other embodiments, the present disclosure is directed to methods for treating ulcerative colitis using a JAK1 inhibitor.
机译:本公开涉及用于治疗克罗恩氏病的方法,并且特别地涉及使用JAK1抑制剂诱导克罗恩氏病的临床缓解和/或内窥镜改善的方法。在某些实施方案中,向患者施用诱导剂量的JAK1抑制剂以诱导克罗恩氏病的临床缓解和/或内窥镜改善,然后其后施用至少一种维持剂量的JAK1抑制剂。在其他实施方案中,本公开内容涉及使用JAK1抑制剂治疗溃疡性结肠炎的方法。

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