机译:晶体(8S,9R)-5-FLUORO-8-(4-Fluorophhenyl)-9-(1-Methyl-1H-1,2,4-triazol-5-YL)-8,9-DIHYDRO-2H-PYRIDO [4,3,2-DE] P HTHALAZIN-3(7H)-1甲磺酸盐。
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摘要
Provided herein are (8S, 9R)-5-fluoro-8-(4-fluorophenyl)-9-(1-methyl-lH-1,2,4-tri azol-5- yl)-8,9-dihydro-2H-pyrido[4,3,2-de]phthalazin-3(7 H)-one tosylate salt forms, including crystalline forms, and methods of their preparation. Pharmaceutical compositions comprising a (8S,9R)-5-fiuoro-8-(4-fluorophenyl)-9-(1-methyl-1 H-1,2,4-triazol-5-yl)-8,9-dihydro-2H- pyrido[4,3,2-de]phthalazin-3(7H)-one tosylate salt are also provided, as are methods of using (8S,9R)-5-fluoro-8-(4-fluorophenyl)-9-(1-methyl-1 H-1,2,4-triazol-5-yl)-8,9-dihydro-2H- pyrido[4,3,2-de]phthalazin-3(7H)-one tosylate salt to treat a disease or condition, such as a cancer.
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