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A new derivative of pyrethroid 2,3-d, pyrethroid, a preparation process and drug synthesis containing Pyrethroid

机译:拟除虫菊酯的新衍生物[2,3-d],拟除虫菊酯及其制备方法和药物合成

摘要

A formula compound (I),R1 and R2 respectively represent h, halo-nr5 or a group of asphalt (C1-C6), linear or separated daughters, etc.; W3 is an alcox (C1-C6), linear or separated daughter-o-tar (c0-c6) - C1, etc.; W4 is cyanogen, cyclization, tar (C1-C6), etc.; R5 and R5 'Each substance is h, or a linear or branched tar group (C1-C6); A1 and A2, each substance is ch or a nitrobenzene atom; C1, C2 and C3, each singular, are cyclopropene, a non cyclopropene group, an arilo group or a foreign matter group. The selected compound is 5 - (2-aminopiridin-4-il) - N - (2-methylbencil) - 2-meth-7h-pirrolo [2,3-d] pirimidin-4-amine. It also refers to a process, its preparation, its drug composition, and its use in the treatment of cancer, neurodegenerative disorders or metabolic disorders.
机译:式(I)的化合物,R1和R2分别代表h,卤代-nr5或一组沥青(C1-C6),直链或分离的子代等。 W3是alcox(C1-C6),线性或分开的子-o-tar(c0-c6)-C1等; W4是氰,环化,焦油(C1-C6)等; R5和R5'中的每个物质均为h,或为直链或支链的焦油基团(C1-C6); A1和A2,每个物质是ch或硝基苯原子; C 1,C 2和C 3各自为单数,为环丙烯,非环丙烯基,芳基或异物基。所选择的化合物是5-(2-氨基哌啶-4-il)-N-(2-甲基苯甲酰)-2-甲基-7h-吡咯并[2,3-d]吡氨基-4-胺。它还指一种方法,其制备,其药物组成及其在治疗癌症,神经退行性疾病或代谢性疾病中的用途。

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