首页>
外国专利>
1,3-DIHYDROIMIDAZOLE-2-THIONE DERIVATIVES FOR USE IN THE TREATMENT OF PULMONARY ARTERIAL HYPERTENSION AND LUNG INJURY
1,3-DIHYDROIMIDAZOLE-2-THIONE DERIVATIVES FOR USE IN THE TREATMENT OF PULMONARY ARTERIAL HYPERTENSION AND LUNG INJURY
展开▼
机译:1,3-二氢咪唑-2-硫酮衍生物用于肺动脉高压和肺损伤的治疗
展开▼
页面导航
摘要
著录项
相似文献
摘要
The present invention relates to compounds of formula I: for use in treating pulmonary arterial hypertension and associated conditions, where R1, R2 and R3 are the same or different and signify hydrogens, halogens, alkyl, alkylaryl, alkyloxy, hydroxy, nitro, amino, alkylcarbonylamino, alkylamino or dialkylamino group; R4 signifies hydrogen, alkyl, -alkylaryl or -alkylheteroaryl; X signifies CH2, oxygen atom or sulphur atom; n is 1, 2 or 3, with the proviso that when n is 1, X is not CH2; and the individual (R)- and (S)-enantiomers or mixtures of enantiomers and pharmaceutically acceptable salts thereof.
展开▼