首页> 外国专利> Antibacterial ionic liquids with 1-alkyl-1-methyl-4-piperidinolium cation and (S)-mandelate anion, method for obtaining them and the application as antibacterial agents

Antibacterial ionic liquids with 1-alkyl-1-methyl-4-piperidinolium cation and (S)-mandelate anion, method for obtaining them and the application as antibacterial agents

机译:具有1-烷基-1-甲基-4-哌啶鎓阳离子和(S)-扁桃酸根阴离子的抗菌离子液体,获得它们的方法和作为抗菌剂的应用

摘要

Antibacterial ion fluids with 1 -alkyl -1 -methyl -4 -piperidine cation and (S)-almond anion of general formula 1 are the subject of the notification,in which R stands for an alkyl base of two to 16 carbon atoms. The notification shall also include the means of receipt,which is based on this,that 1 -alkyl -1 -methyl -4 -piperidine oil bromide of a general formula 2,in which R stands for an alkyl base of two to 16 carbon atoms,is dissolved in methanol,or ethanol,or 1 -propanol,or 2 -propanol,followed by the addition of lithium or potassium salt or sodium (S)-almolic acid in molar ratio from 1 to 1,1,the system is then mixed in temperature from 15 to 40oC,favourable 20oC,between twenty minutes and one hour,favourable thirty minutes,then the extracted inorganic salt is removed,and then evaporate the solvent from the transfer,and the rest dry. The notification shall also cover the use of ion fluids as antibacterial agents.
机译:具有1-烷基-1-甲基-4-哌啶阳离子和通式1的(S)-杏仁阴离子的抗菌离子流体是本公开的主题,其中R代表2至16个碳原子的烷基。通知还应包括基于此的接收方式,即通式2的1-烷基-1-甲基-4-哌啶油溴化物,其中R表示2至16个碳原子的烷基将其溶于甲醇或乙醇或1-丙醇或2-丙醇中,然后以1:1的摩尔比加入锂或钾盐或钠(S)-羟甲基酸,然后制得在15至40oC,有利于20oC的温度下混合,在20分钟至1小时,有利于30分钟的时间内混合,然后除去提取的无机盐,然后从转移液中蒸发掉溶剂,其余部分干燥。该通知还应涵盖离子液体作为抗菌剂的使用。

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