Method for obtaining bicyclic imines of (4aR,8aR)-4a,5,6,7,8,8a-hexahydroquinoxaline-2(1H)-one and 6,8-dimethylquinoxaline-2(1H)-one

摘要

The scope of the notification is the production method (4aR,8aR)-4a,5,6,7,8,8a -hexahydroquinoxaline -2 (1H)-one (formula 1) and 6,8 -dimethylcokinoxanoline -2 (1H)-one (formula 2) whereby the vitamin bisamine of the generic formula 1 in which R stands for cyclohexane or 3,5 -dimethylbenzene is subjected reaction with a 50%solution of ethyl glycolate in toluene, of a general formula 2, at room temperature (293 K), over time from 24 to 72 h, and then the product is purified.