kits for non invasive detection of glucose in saliva based on modified - graphene electrode.

摘要

the invention provides a nanotechnology based non-invasive device for continuous measurement of glucose levels in saliva.a method of the invention includes collecting the saliva sample by placing the one time use the strip into the mouth of the patient for a few seconds and placing the above-mentioned strip into the ha.device for the ndheld glucose reading. the method of the invention is performed by using a kit of the invention.the kit comprises a strip including an amperometric glucose biosensor and a reader for glucose screening by comparing the current readout with a standard calibration curve or by automatically converting the current flow generated by the tested sample to units of glucose concentration.the biosensor comprises a graphene or graphene has the functionalized redox electrode having a glucose oxidase layer for the oxidation of glucose.a reference electrode and a counter electrode. the electrodes are formed on an ali insulating substrate.measurement of saliva glucose concentration with the kit provides a non-invasive probe of a patient's blood glucose level and a linear relationship exists between blood glucose concentration and itsliva glucose concentration.