首页> 外国专利> ANTI¿PCSK9 INHIBITORY ANTIBODIES FOR TREATING PATIENTS WITH HYPERLIPIDEMIA UNDERGOING LIPOPROTEIN APHERESIS

ANTI¿PCSK9 INHIBITORY ANTIBODIES FOR TREATING PATIENTS WITH HYPERLIPIDEMIA UNDERGOING LIPOPROTEIN APHERESIS

机译:抗PCSK9脂蛋白血症性高脂血症患者的治疗抑制剂

摘要

The present invention provides methods for reducing or eliminating a patient's need for lipoprotein apheresis therapy. The methods of the present invention comprise administering to a patient a pharmaceutical composition comprising a PCSK9 inhibitor. In certain embodiments, the PCSK9 inhibitor is an anti-PCSK9 antibody. The methods of the present invention are useful for treating patients with hyperlipidemia and related conditions who are currently being treated with a therapeutic regimen comprising lipoprotein apheresis (e.g., LDL apheresis or Lp(a) apheresis).
机译:本发明提供了减少或消除患者对脂蛋白单采疗法的需求的方法。本发明的方法包括向患者施用包含PCSK9抑制剂的药物组合物。在某些实施方案中,PCSK9抑制剂是抗PCSK9抗体。本发明的方法可用于治疗高脂血症和相关病症的患者,这些患者目前正在接受包括脂蛋白单采术(例如LDL单采术或Lp(a)单采术)的治疗方案的治疗。

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