Disclosed is a protective agent for ancient bone resources, which is prepared by mixing a binder, propylene glycol, an antioxidant enzyme mimic, a plant extract antioxidant, an antibacterial agent, a preservative, a lysozyme and water. The binder therein comprises either of a water soluble protein and a water soluble starch. The synergistic effect of the components of the protective agent is enhanced through the coordination of different substance ingredients and contents thereof. The protective agent has excellent reversibility, protection, oxidation resistance and antibacterial ability after being sprayed on ancient bones. The protective agent does no harm to the human body and guarantees the safety of operators and visitors.
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