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ENHANCED DELIVERY OF VIRAL PARTICLES TO THE STRIATUM AND CORTEX
ENHANCED DELIVERY OF VIRAL PARTICLES TO THE STRIATUM AND CORTEX
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机译:增强病毒颗粒向纹状体和皮层的输送
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摘要
ENHANCED DELIVERY OF VIRAL PARTICLES TO THE STRIATUM AND CORTEX Provided herein are novel methods for delivering recombinant adeno-associated viral (rAAV) particles to 5 the central nervous system of a mammal (e.g., a human). In aspects, the methods involve administering rAAV particles containing a heterologous nucleic acid to the striatum and causing expression of the heterologous nucleic acid in at least the cerebral cortex and the striatum of the mammal. [Figure 5B] 10
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