Modified release therapeutic systems for the oral administration of curcumin in the treatment of intestinal disorders

摘要

Colon specific delayed release monolithic pharmaceutical compositions comprising: a) a nucleus with a monolithic matrix comprising hydroxypropyl methylcellulose where curcumin is dispersed; b) a gastroresistant coating of the core a), where the weight ratio of curcumin to hydroxypropyl methylcellulose is in the range of 4: 1 to 2: 1