Bacteriocin derived from lactobacillus rhamnosus

摘要

A basic antimicrobial peptide comprising an amino acid sequence shown in SEQ ID NO: 1 or SEQ ID NO: 2 in the SEQUENCE LIST or with the same amino acid sequence as shown in SEQ ID NO: 1 or in SEQ ID NO: 2 in the SEQUENCE LISTING, except that one to four amino acids are deleted, replaced, inserted and / or added, in which the basic antimicrobial peptide is antimicrobial for cariogenic bacteria, periodontal disease bacteria and Candida and It has an isoelectric point of not less than 12, for use in prophylaxis, improvement and / or therapy of oral diseases.