Determination of lipocalin associated with neutrophil gelatinase (NGAL) as a diagnostic marker for renal disorders

摘要

A method of monitoring the onset of a renal disorder in a human being, said method comprises the steps of i) determining the concentration of lipocalin associated with human neutrophil gelatinase (NGAL) in a sample of a human body fluid, ii) repeat step i) in an additional sample of body fluid from the same human being taken after 24 hours or less; and iii) evaluate whether or not the human being has developed a renal disorder, or is about to develop a renal disorder, by comparing the concentrations obtained in stage i) and ii), where a rise in the concentration of NGAL of 50 ng / ml or more in the additional sample is indicative that the human being has developed a renal disorder, or is about to develop a renal disorder