Methods of treatment of non-histamine pruritus in mammals

摘要

RS-norketotifen or one of its pharmaceutically acceptable salts for use in a method for treating non-histaminergic pruritus in a mammal, said method comprising administering orally said Nitorketotifen or one of its pharmaceutically acceptable salts for said mammal, thereby reducing the mammal the desire to scratch, in which non-histaminergic pruritus is resistant to treatment with selective histamine H-1 receptor inhibitors, histamine H-2 receptor inhibitors and histamine H-4 receptor inhibitors, and that non-histaminergic pruritus is associated with a dermal disorder, a nervous disorder or a systemic disorder.