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Use of magnesium stearate in dry powder formulations for inhalation
Use of magnesium stearate in dry powder formulations for inhalation
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机译:硬脂酸镁在干粉制剂中的吸入用途
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摘要
Use of magnesium stearate in powder formulations for inhalation comprising alpha-lactose monohydrated carrier particles and an active ingredient carrying a hydrolysis group selected from the group consisting of carbonate, carbamate and ester, to inhibit or reduce chemical degradation of said active ingredient, in which the carrier particles have a mass diameter between 80 and 500 microns and where magnesium stearate is present in an amount between 0.05 and 1.5% based on the total weight of the carrier and covers the surface of the carrier particles to a degree greater than 60%.
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