METHODS FOR PURIFYING TRANS-(-)-DELTA9-TETRAHYDROCANNABINOL AND TRANS-(+)-DELTA9-TETRAHYDROCANNABINOL

摘要

Methods for making trans-(-)-.DELTA.9-tetrahydrocannabinoI and trans-(+)- .DELTA.9-tetrahydrocannabinol are disclosed herein. In one embodiment, a trans-(-)-.DELTA.9-tetrahydrocannabinoI composition is prepared by allowing a composition comprising (+)-.DELTA.9- tetrahydrocannabinol to separate on a chiral stationary phase to provide a trans-(-)-.DELTA.9-tetrahydrocannabinoI composition comprising at least about 99% by weight of trans-(-)-.DELTA.9-tetrahydrocannabinol based on the total amount of trans-(-)-.DELTA.9-tetrahydrocannabinol and trans-(+)-.DELTA.9- tetrahydrocannabinol. The invention also relates to methods for treating or preventing a condition such as pain comprising administering to a patient in need thereof an effective amount of a trans-(-)-.DELTA.9- tetrahydrocannabinoI having a purity of at least about 98% based on the total weight of cannabinoids.