NOVEL CARBOXYLIC ACID COMPOUNDS USEFUL FOR INHIBITING MICROSOMAL PROSTAGLANDIN E2 SYNTHASE-1

摘要

The present invention provides compounds of Formula 1, or a pharmaceuticallyacceptablesalt, thereof,(see formula I)where R, X, A, E, and G are as described herein, methods of preparing thecompounds, anduse of the compounds to treat pain and/or inflammation.