METHOD FOR MATURATION OF RETINAL TISSUE CONTAINING CONTINUOUS EPITHELIUM

摘要

The present invention provides a method for retaining the continuous epithelial structure of retinal tissue. The method includes culturing a retinal tissue in a culture medium containing: a methyl group donor or a substrate of a methyl group donor at a concentration that inhibits cellular differentiation of neuroretinal precursor cells; and a neurite outgrowth inhibitor at a concentration that inhibits neurite outgrowth.