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FULLY HUMANIZED ANTI-B CELL MATURATION ANTIGEN (BCMA) SINGLE-CHAIN ANTIBODY AND USE THEREOF

机译：完全人源化抗B细胞成熟抗原（BCMA）单链抗体及其用途

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摘要

The present invention relates to a novel antibody and antibody fragment specifically binding to the B cell maturation antigen (BCMA), and relates in particular to a fully human single chain variable fragment (scFv). The present invention also relates to a nucleic acid encoding the antibody, a vector, a host cell expressing the nucleic acid, a composition including the antibody, and a use of the composition in treatment and diagnosis.

机译：本发明涉及与B细胞成熟抗原（BCMA）特异性结合的新型抗体和抗体片段，尤其涉及完全人单链可变片段（scFv）。本发明还涉及编码抗体的核酸，载体，表达该核酸的宿主细胞，包含该抗体的组合物以及该组合物在治疗和诊断中的用途。

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公开/公告号CA3081125A1

专利类型
公开/公告日2019-08-08

原文格式PDF
申请/专利权人 INNOVENT BIOLOGICS (SUZHOU) CO. LTD.;
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申请/专利号CA20193081125
发明设计人 LI ZHIYUAN;ZHAI TIANHANG;ZHOU SHUAIXIANG;YU DECHAO;
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申请日2019-02-01
分类号C07K16/28;A61P35;A61P37/02;C07K14/725;C07K19;C12N15/12;C12N15/13;C12N15/62;G01N33/574;G01N33/68;
国家 CA
入库时间 2022-08-21 11:58:27

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