THE PRIMARY SITE OF METASTATIC CANCER IDENTIFICATION METHOD AND SYSTEM THEREOF

摘要

The present disclosure provides a developing method of candidate probes and a using method thereof. Specifically, the candidate probes are capable binding specific genes and further identifying the primary site of a metastatic cancer in a subject in need thereof. Briefly, the developing method comprises the steps of: (a) using a chip to generate gene expressions of metastasis cancer samples with well known primary sites; (b) using a processing module to compare the gene expressions of metastasis cancer samples; and (c) developing candidate probes based on the previous comparing results. The using method comprises the steps of: (a') using the previous candidate probes to detect the relative gene expression in a test sample with unknown primary site; and (b') using a processing module to predict the primary site of the test sample. Moreover, the present disclosure further provides a system used to conduct the above method, and the system comprises a detecting chip including an array with the candidate probes and a processing module.