METHODS OF TREATING EPILEPSY AND NEURODEVELOPMENTAL DISORDERS

摘要

The present invention is directed to, in part, methods of preventing and/or treating a disease or condition relating to aberrant function of a voltage-gated, sodium ion channel, for example, abnormal late/persistent sodium current. In some embodiments, methods of treating a neurodevelopmental disorder (e.g., epilepsy) comprising administering to a subject in need thereof a compound disclosed herein (e.g., a compound of Formula (I), (I-a), or (I-b), e.g., eleclazine) are provided.